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Fig. 2.

Fig. 2.

Cer species in the plasma of Ldlr−/− mice fed an atherogenic diet supplemented with inulin or cellulose (control). After 10 days of feeding (A); after 12 weeks of feeding (B); and the ratios of Cer16:0/24:0 after 10 days and 12 weeks of feeding (C). Cer and SM levels were detected by UHPLC-Q Exactive MS. Mean ± SEM is shown (n = 9–10 per group). ****P < 0.0001, ***P < 0.001, **P < 0.01 (unpaired Student’s t-test).