Fig. 6.

Changes in plasma lipoprotein-associated Cer after 12 weeks of feeding an inulin- or cellulose-supplemented (control) atherogenic diet to Ldlr^−/− mice. Plasma samples from three mice in each group were pooled and lipoproteins including VLDL, LDL, and HDL were fractionated using fast protein LC. Cers in samples were detected by UHPLC-Q Exactive MS. A: Comparison of individual Cer species in the total VLDL-, LDL-, and HDL-associated fractions of inulin and control diet-fed mice. B–F: Levels of individual Cer species present in each fraction obtained from fast protein LC.