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. Author manuscript; available in PMC: 2020 Dec 3.
Published in final edited form as: Structure. 2019 Oct 8;27(12):1855–1861.e3. doi: 10.1016/j.str.2019.09.008

Figure 4. Model of channel opening and association with other synthase subunits.

Figure 4.

(A) Model of BcsC’s channel opening during cellulose translocation. The extracellular gating and EL6 loops are shown in red and yellow, respectively. The periplasmic domain of BcsC has been omitted, for clarity.

(B) Bacterial cellulose synthase components span the cell envelope. BcsA, -B, -C, and –Z are conserved in Gram-negative cellulose synthase complexes. BcsG, together with additional subunits, is prevalent among Enterobacteria. PDB coordinates of the depicted structures are: 4P00 (BcsAB), 5OJH (BcsG), 3QXF (BcsZ), and 5XW7 (TRP1–6). IM/OM: Inner and Outer Membrane.