Skip to main content
. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Neurobiol Dis. 2019 Aug 30;132:104602. doi: 10.1016/j.nbd.2019.104602

Figure 3.

Figure 3.

Increased Repetitive Self-grooming but normal Ambulation and Anxiety in PC-specific L7-DKO Mice. (A) L7-DKO mice showed a significant increase in total time spent in grooming and in the number of grooming episodes as compared to L7-control mice (top panel). We detected a moderate increase in fine movements in open field in L7/DKO mice, further suggesting increase in repetitive behaviors (bottom panel); Student’s t test. (B) Open field and rotarod tests showed normal ambulatory activities and motor learning and balance in L7-DKO mice; upper B panel, Student’s t test; bottom B panel, Factorial Repeated Measures ANOVA. (C) O-maze and Light/Dark box tests indicated no differences in anxiety levels between L7-DKO and L7-control mice; Student’s t test; *P<0.05; n=10–11 mice per group.