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(A–D) The effects of PYT HCl, PIT HCl, DBT HCl, 2-MT HCl, and METH on the locomotor activity (n=10 animals per group). (E) mRNA expression levels of 5-HTR1a in the mouse prefrontal cortex (n=6 animals per group). Mice were treated with vehicle, PYT HCl, PIT HCl, DBT HCl, 2-MT HCl, and METH. Values are (mean ± SEM). *p<0.05, **p<0.01, ***p<0.001 significantly different from the veh group (Dunnett’s posttest).
