Table 5.
Cox proportional hazards model analysis of the clinicopathological and treatment features in terms of distant metastasis-free survival
| Feature | Relative risk | 95% CI | p |
|---|---|---|---|
| Age, years | <0.001 | ||
| <35 | 1.00 | ||
| ≥35 | 0.68 | 0.56–0.84 | |
| Menopausal status | 0.263 | ||
| Premenopausal | 1.00 | ||
| Postmenopausal | 1.08 | 0.94–1.23 | |
| Tumor size | <0.001 | ||
| T1 | 1.00 | ||
| T2 | 1.55 | 1.33–1.82 | |
| T3 | 2.49 | 2.05–3.03 | |
| Multifocality/multicentricity | 0.001 | ||
| Yes | 1.00 | ||
| No | 0.72 | 0.59–0.88 | |
| Histological type | 0.392 | ||
| ILC | 1.00 | ||
| IDC | 0.96 | 0.77–1.19 | |
| IDLC | 1.14 | 0.83–1.57 | |
| Axillary lymph node status | <0.001 | ||
| Negative | 1.00 | ||
| Positive | 2.41 | 1.99–2.93 | |
| Surgery | 0.661 | ||
| Mastectomy | 1.00 | ||
| Breast-conserving | 0.95 | 0.76–1.19 | |
| Chemotherapy | 0.301 | ||
| Yes | 1.00 | ||
| No | 0.89 | 0.71–1.11 | |
| Hormonal therapy | <0.001 | ||
| Yes | 1.00 | ||
| No | 1.36 | 1.20–1.55 | |
| Radiotherapy | 0.068 | ||
| Yes | 1.00 | ||
| No | 0.83 | 0.67–1.01 |
CI: confidence interval; ILC: invasive lobular carcinoma; IDC: invasive ductal carcinoma; IDLC: mixed invasive ductal and lobular carcinoma