Table 2.

Ongoing Clinical Trials in Systemic Sclerosis-Related Pulmonary Arterial Hypertension and Pulmonary Arterial Hypertension with Planned Enrollment of Connective Tissue Disease-Related Pulmonary Arterial Hypertension as of August 2019

Trial ID	Trial Phase	Study Design	Intervention	Estimated Enrollment	Study Start Date
NCT0298108265	1	Double-blind Placebo-controlled	Dimethyl fumarate	34	12/2016
NCT0108654066	2	Double-blind Placebo-controlled	Rituximab	58	06/2011
NCT0268251167	2	Double-blind Placebo-controlled	Ifetroban	34	01/2017
NCT0372639868	2 and 3	Open label	Macitentan	26	09/2018
NCT0363021169	2	Open label	Autologous stem cell transplant	8	07/2018
NCT0265735670	3	Double-blind Placebo-controlled	Bordoxolonemethyl	200	10/2016
NCT0362668871	3	Double-blind Placebo-controlled	Ralinepag	700	08/2018
NCT0344952472	2	Double-blind Placebo-controlled	CXA-10	96	08/2018