Figure 1e.

Progression of fibrosis in viral hepatitis. Photomicrographs (original magnification, ×40; trichrome stains) of histologic sections from liver biopsy specimens show the progression of fibrosis in viral hepatitis: normal portal triads with no signs of fibrosis (stage F0) (a), portal fibrous expansion (stage F1) (b), thin fibrous septa emanating from portal triads (stage F2) (c), fibrous septa bridging portal triads and central veins (stage F3) (d), and cirrhosis (stage F4) (e), which appears as nodules of liver parenchyma separated by thick fibrous bands.