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. Author manuscript; available in PMC: 2020 Jan 2.
Published in final edited form as: ACS Nano. 2016 Oct 19;10(12):10636–10651. doi: 10.1021/acsnano.6b02231

Figure 3.

Figure 3.

Treatment with AuNPs alters secretory profile of pancreatic cancer and stellate cells. (A) Relative levels of significantly (*p ≤ 0.05) altered angiogenesis-related proteins in AsPc1 and Panc-1 conditioned media upon treatment with 25 μg/mL dose of 20 nm AuNP for 48 h. Folds are with respect to untreated controls. (B) qRT-PCR analysis of altered angiogenesis-related proteins in untreated and 25 μg/mL AuNP-treated AsPc1 cells analyzed 48 h post-treatment. GAPDH was used as an internal control. (C) Relative levels of significantly (p ≤ 0.05) altered angiogenesis-related proteins in iTAF and CAF19 conditioned media upon treatment with 25 μg/mL of 20 nm AuNPs for 48 h. Folds are with respect to untreated controls. (D) qRT-PCR analysis of altered angiogenesis-related proteins in untreated and 25 μg/mL AuNP-treated iTAF and CAF19 cells analyzed 48 h post-treatment. GAPDH was used as an internal control. Data represent mean ± s.d. of three individual experiments (n = 3).