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. Author manuscript; available in PMC: 2020 Jan 2.
Published in final edited form as: J Am Chem Soc. 2019 Apr 4;141(15):6224–6233. doi: 10.1021/jacs.8b13376

Table 1.

Relaxivities of MR probes at 1.41 T (37 °C) and 7 T (25 °C)

MR Probe r1 at 1.41 T
(mM−1 s−1)		 r2 at 1.41 T
(mM−1 s−1)		 r1 at 7 T
(mM−1 s−1)		 r2 at 7 T
(mM−1 s−1)
CP1 8.1 9.7 5.8 10.9
CP1+ caspase3a 16.7 19.7 5.9 30.6
CP1-ctrl 8.8 10.4 8.0 20.9
CP1-ctrl + Caspase3 8.1 10.8 6.2 18.7
Gad-AIE 18.9 30.5 5.8 32.8
a

Approximately 60 % conversion was observed after 200 μM CP1 was incubated with caspase-3 (0.4 μg/mL) overnight.