Table 2. Distribution of CD-predisposing HLA-DQB1 alleles in the bone marrow healthy donors in Kazakhstan (N: number of carriers; %: carrier percentage of the whole cohort of donors).

Class II MHC β chain	HLA-DQ B1*(1)	HLA-DQ B1*(2)	N	%
	02:01	02:01	86	2.16
	02:01	02:02	43	1.08
	02:02	02:02	21	0.53
βDQ2+βDQ2		Sub-Total	150	3.77
	02:01	03:01	275	6.91
	02:01	03:03	75	1.88
	02:01	03:04	2	0.05
	02:01	03:05	1	0.03
	02:01	04:01	14	0.35
	02:01	04:02	35	0.88
	02:01	04:04	1	0.03
	02:01	04:19	1	0.03
	02:01	05:01	119	2.99
	02:01	05:02	52	1.31
	02:01	05:03	49	1.23
	02:01	05:04	9	0.23
	02:01	05:09	1	0.03
	02:01	06:01	53	1.33
	02:01	06:02	129	3.24
	02:01	06:03	94	2.36
	02:01	06:04	27	0.68
	02:01	06:05	1	0.03
	02:01	06:09	15	0.38
	02:02	03:01	91	2.29
	02:02	03:03	9	0.23
	02:02	04:01	5	0.13
	02:02	04:02	14	0.35
	02:02	05:01	36	0.90
	02:02	05:02	19	0.48
	02:02	05:03	9	0.23
	02:02	06:01	12	0.30
	02:02	06:02	35	0.88
	02:02	06:03	18	0.45
	02:02	06:04	8	0.20
	02:02	06:09	8	0.20
βDQ2		Sub-Total	1217	30.58
	02: 01	03:02	101	2.54
	02:02	03:02	32	0.80
βDQ2+βDQ8		Sub-Total	133	3.34
	03:02	03:02	28	0.70
βDQ8+βDQ8		Sub-Total	28	0.70
	03:02	02:03	2	0.05
	03:02	03:03	37	0.93
	03:02	03:04	3	0.08
	03:02	03:05	4	0.10
	03:02	04:01	10	0.25
	03:02	04:02	18	0.45
	03:02	05:01	83	2.09
	03:02	05:02	20	0.50
	03:02	05:03	14	0.35
	03:02	05:04	3	0.08
	03:02	06:01	23	0.58
	03:02	06:02	59	1.48
	03:02	06:03	37	0.93
	03:02	06:04	16	0.40
	03:02	06:09	9	0.23
βDQ8		Sub-Total	338	8.49
TOTAL			1,866	46.88%