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. 2020 Jan 2;17(1):e1002997. doi: 10.1371/journal.pmed.1002997

Table 2. Effects of intervention on control of hypertension (primary outcome) and prescription of antihypertensive medication (secondary outcome) in people with hypertension: complete case analysis.

Outcome Number of participants Change from baseline to follow-up* P value Adjusted odds ratio (95% CI) P value
Intervention UC Intervention UC
Overall
    Control of hypertension 459 1,011 93 (20.3) 96 (9.5) <0.001
  • 1.6 (1.2–2.1)

0.001
    Prescribed antihypertensive medication 459 1,012 57 (12.4) 100 (9.9) 0.14 1.2 (0.8–1.9) 0.34
Women
    Control of hypertension 280 596 52 (18.6) 49 (8.2) <0.001 1.6 (1.1–2.2) 0.01
    Prescribed antihypertensive medication 280 597 38 (13.6) 45 (7.5) 0.004 1.5 (0.9–2.2) 0.09
Men
    Control of hypertension 178 411 41 (23.0) 48 (11.7) <0.001 1.6 (1.1–2.5) 0.02
    Prescribed antihypertensive medication 178 411 19 (10.7) 54 (13.1) 0.40 0.9 (0.5–1.7) 0.85

There are 4 missing observations for sex in the UC group and 1 in the intervention group.

*Change in control of hypertension was obtained by subtracting the number of people with control of hypertension at baseline from the number with control at follow-up. The same approach was applied to prescription of antihypertensive medication. Positive number demonstrates improvement.

Odds ratios obtained using mixed effects logistic regression, clustered by village and study region. For control of hypertension, the dependent variable was control of hypertension at follow-up, with adjustment for control of hypertension at baseline (ICC: overall, 0.002; women, 0.003; men, 0.008). The same approach was applied to prescription of antihypertensive medication (ICC: overall, 0.04; women, 0.02; men, 0.09).

A person who did not have blood pressure measured at follow-up had details of medications, and so there is an extra observation for the latter analysis.

ICC, intraclass correlation coefficient; UC, usual care.