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. 2019 Dec 12;19(8):1–108.

Table 8:

Time in Target Glucose Range and Hypoglycemia and Glucose Variability for People With Type 2 Diabetes

Group Means Difference Between Flash and SMBG (% Change) Difference in End-of-Study Adjusted Means Between Flash and SMBG (95% CI) P Value
Flash SMBG
Baseline Study End Baseline Study End
Hours in target glucose range (3.9–10.0 mmol/L) within 24 hours
13.9 13.6 13.5 13.2 1.1% 0.2 (−0.94, 1.34) .7925
Hours above target glucose range (> 13.3 mmol/L) within 24 hours
3.1 3.5 3.9 3.9 2.1% 0.1 (−0.80 to 1.00) .8729
Hours in hypoglycemia (< 3.9 mmol/L) within 24 hours
1.3 0.59 3.44 3.27 −38.0% −1.24 (−1.71 to −0.77) < .0001
Hours in hypoglycemia at night (11 pm-6 am) within 7 hours
0.55 0.23 0.49 0.51 −54.3% −0.29 (−0.45, −0.13) .0001
Mean hypoglycemia events < 3.9 mmol/L (70 mg/dL) within 24 hours
0.64 0.38 0.63 0.53 27.7% −0.16 (−0.29 to −0.03) .0164
Hours in hyperglycemia (> 13.3 mmol/L) within 24 hours
3.1 3.5 3.9 3.9 2.1% 0.1 (−0.80, 1.00) .8729
Mean amplitude of glucose excursiona
128 125 131 131 NA −4.0 (−10.47 to −2.47) .1909
Blood glucose risk indexa
9.5 9.9 10.4 10.5 NA 0.0 (−1.37 to 1.37) .9431
Coefficient of variation in glucose, %a
34.1 31.4 33.1 33.0 NA −2.26 (−3.65 to −0.868) .0017
Low blood glucose risk indexa
1.1 0.60 1.0 0.90 NA −0.30 (−0.52 to −0.08) .0029
Standard deviation of glucose, mg/dLa
56 54 56 56 NA −1.67 (−4.51 to −1.17) .2538
Continuous overall net glycemic action, 2 hours, mg/dLa
49 47 50 51 NA −3.0 (−5.55 to −0.45) .0385
Continuous overall net glycemic action, 4 hours, mg/dLa
61 57 61 64 NA −5.0 (−9.31 to −0.69) .0133
Continuous overall net glycemic action, 6 hours, mg/dLa
63 58 62 65 NA −8.0 (−13.88 to −2.12) .0046

Abbreviations: CI, confidence interval; NA, not applicable; SMBG, self-monitoring of blood glucose.

a

A scale for measuring glucose variability.

Source: Haak et al.33