Table 9:
Subgroup Analyses of Time in Target Glucose Range and Hypoglycemia Among People With Type 2 Diabetes
| Author, Year | Group Means | Difference Between Flash and SMBG (% Change) | Difference in End-of-Study Adjusted Means Between Flash and SMBG (95% CI)a | P Value | |||
|---|---|---|---|---|---|---|---|
| Flash | SMBG | ||||||
| Baseline | Study End | Baseline | Study End | ||||
| Hours in target glucose range (3.9–10.0 mmol/L) within 24 hours | |||||||
| Haak et al, 201733 (< 65 years) | 13.3 | 13.3 | 12.7 | 12.7 | NA | 0.3 (−1.19 to 1.79) | .6777 |
| Haak et al, 201733 (≥ 65 years) | 14.9 | 14.2 | 14.9 | 14.0 | NA | 0.3 (−1.44 to 2.04) | .7476 |
| Hours in hypoglycemia (< 3.9 mmol/L) within 24 hours | |||||||
| Haak et al, 201733 (< 65 years) | 1.17 | 0.64 | 0.98 | 0.96 | −35.4% | −0.37 (−0.70 to −0.04) | .0279 |
| Haak et al, 201733 (≥ 65 years) | 1.53 | 0.49 | 1.26 | 1.03 | −55.9% | −0.60 (−1.03 to −0.17) | .0083 |
| Hours in hyperglycemia (> 13.3 mmol/L) within 24 hours | |||||||
| Haak et al, 201733 (< 65 years) | 3.5 | 3.7 | 4.4 | 4.2 | 1.9% | −0.1 (−1.33 to 1.13) | .9063 |
| Haak et al, 201733 (≥ 65 years) | 2.40 | 3.20 | 3.0 | 3.4 | 3.7% | 0.1 (−1.29 to 1.49) | .8791 |
Abbreviations: CI, confidence interval; NA, not applicable; SMBG, self-monitoring of blood glucose.
a
Confidence intervals were computed by the authors of this health technology assessment using the standard error reported in the primary study.