Table 4.
Note.—Unless otherwise indicated, results change little if the five patients who underwent 3.0-T MR imaging are included in the analysis; change in AUC was no more than 0.01, and changes in sensitivity and specificity (including the 95% confidence interval) were no more than 2.7% with fixed cutoff values.
Data are maximum likelihood estimate ± standard error.
Empirical sensitivity and specificity values were calculated from the data and fall close to the fitted ROC curve. Data in parentheses are raw data, and data in brackets are 95% confidence intervals, which are exact binomial estimates.
Example of image feature cutoff values that yield the listed sensitivity and specificity values.
Two cases were excluded from the analysis because of image artifacts.
The combination of 10th percentile ADC, average ADC, and T2 skewness with a linear discriminant analysis classifier. P values are for AUC comparison with 10th percentile ADC alone and were .06 for both techniques.