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Sequence around ISRE and BCP region of HBV 4 constructs used in the study. ISREwtb, wildtype genotype B ISRE; ISREmt, a dysfunctional mutation on ISRE, ISREmtc, genotype B ISRE mutated to genotype C ISRE; ISREmtbcp, extra BCP 1762/1764 double mutation beside ISREmtc.
