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. 2019 Nov 20;132(22):2716–2723. doi: 10.1097/CM9.0000000000000513

Figure 1.

Figure 1

Effects of endostatin overexpression on cardiac hypertrophy in Ang II-treated rats under transthoracic echocardiography. Endostatin overexpression attenuated the increases in LV mass, LV mass/BW, IVSd, IVSs, LVPWd, LVPWs in Ang II-treated rats. Results are expressed as mean ± SE, n = 6. ∗P < 0.05 vs. the Ad-GFP group; †P < 0.05 vs. the Ad-endostatin group. Ad-GFP group: Rats treated with adenovirus expressing green fluorescent protein; Ang II group: Rats treated with Ang II; Ad-endostatin group: Rats treated with adenovirus expressing endostatin; Ang II + Ad-endostatin group: Rats treated with Ang II and adenovirus expressing endostatin. Ad-GFP: Adenovirus-green fluorescent protein; Ang II: Angiotensin II; BW: Body weight; IVSd: Interventricular septal thickness in diastole; IVSs: Interventricular septal thickness in systole; LV: Left ventricle; LVPWd: Left ventricular posterior wall thickness in diastole; LVPWs: Left ventricular posterior wall thickness in systole; SE: Standard error.