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. 2019 Nov 20;132(22):2716–2723. doi: 10.1097/CM9.0000000000000513

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Copyright © 2019 The Chinese Medical Association, produced by Wolters Kluwer, Inc. under the CC-BY-NC-ND license.

This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0

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Effects of endostatin overexpression on cardiac fibrosis in Ang II-treated rats (Masson staining, bar: 100 μm). Endostatin overexpression attenuated the increase in cardiac fibrosis levels in Ang II-treated rats. Results are expressed as mean ± SE, n = 6. ^∗P < 0.05 vs. the Ad-GFP group; ^†P < 0.05 vs. the Ad-endostatin group. Ad-GFP group: Rats treated with adenovirus expressing green fluorescent protein; Ang II group: Rats treated with Ang II; Ad-endostatin group: Rats treated with adenovirus expressing endostatin; Ang II + Ad-endostatin group: Rats treated with Ang II and adenovirus expressing endostatin. Ad-GFP: Adenovirus-green fluorescent protein; Ang II: Angiotensin II; SE: Standard error.