Table 1.
Zilver PTX RCT demographics and baseline lesion characteristics
| Characteristic | DES | PTA/BMS | p value |
|---|---|---|---|
| Age (years) | 67.6 ± 9.6 (336) | 68.2 ± 11.2 (143) | 0.58 |
| Gender | 0.60 | ||
| Male | 65.8% (221/336) | 62.9% (90/143) | |
| Female | 34.2% (115/336) | 37.1% (53/143) | |
| Ethnicity | 0.96 | ||
| Asian | 12.8% (38/298) | 14.0% (17/121) | |
| Black/African-American | 12.1% (36/298) | 10.7% (13/121) | |
| Hispanic/Latino | 6.7% (20/298) | 5.8% (7/121) | |
| White/Caucasian | 68.5% (204/298) | 69.4% (84/121) | |
| Body mass index | 28.3 ± 5.2 (336) | 28.4 ± 6.0 (143) | 0.87 |
| Diabetes | 45.2% (152/336) | 46.9% (67/143) | 0.76 |
| Diabetes type | 0.54 | ||
| Type I | 15.8% (24/152) | 11.9% (8/67) | |
| Type II | 84.2% (128/152) | 88.1% (59/67) | |
| Hypercholesterolemia | 75.0% (252/336) | 67.8% (97/143) | 0.12 |
| Hypertension | 87.5% (294/336) | 80.4% (115/143) | 0.049 |
| Carotid artery disease | 19.0% (64/336) | 18.9% (27/143) | > 0.99 |
| Renal disease | 9.5% (32/336) | 11.9% (17/143) | 0.51 |
| Pulmonary disease | 18.5% (62/336) | 14.7% (21/143) | 0.36 |
| Congestive heart failure | 11.3% (38/336) | 11.2% (16/143) | > 0.99 |
| Previous cardiac arrhythmia | 9.8% (33/336) | 16.1% (23/143) | 0.06 |
| Previous MI | 20.5% (69/336) | 15.4% (22/143) | 0.21 |
| Smoking status | 0.54 | ||
| Never | 14.6% (49/336) | 15.4% (22/143) | |
| Quit | 54.2% (182/336) | 51.7% (74/143) | |
| Still smokes | 31.3% (105/336) | 32.2% (46/143) | |
| Unknown | 0% (0/336) | 0.7% (1/143) | |
| Rutherford 0–3 | 92.0% (309/336) | 89.4% (126/141) | 0.38 |
| Rutherford 4–6 | 8.0% (27/336) | 10.6% (15/141) | |
| Lesion length (mm) | 55.8 ± 41.1 (354) | 51.8 ± 39.8 (149) | 0.32 |
| Total occlusion | 31.1% (110/354) | 28.2% (42/149) | 0.60 |
| Proximal RVD (mm) | 5.1 ± 1.0 (350) | 5.0 ± 0.9 (148) | 0.65 |
| Distal RVD (mm) | 5.0 ± 1.0 (350) | 5.0 ± 1.1 (148) | 0.98 |
| MLD in lesion (mm) | 1.0 ± 0.9 (350) | 1.1 ± 0.9 (148) | 0.48 |
| Percent diameter stenosis (%) | 79.5 ± 17.1 (350) | 78.5 ± 16.7 (148) | 0.59 |
| Calcification | 0.08 | ||
| None | 2.8% (10/354) | 5.4% (8/149) | |
| Little | 30.2% (107/354) | 38.3% (57/149) | |
| Moderate | 30.5% (108/354) | 22.1% (33/149) | |
| Severe | 36.4% (129/354) | 34.2% (51/149) | |
| Other stenosis in artery | 0.049 | ||
| None | 51.1% (180/352) | 50.3% (75/149) | |
| ≤ 50% | 32.1% (113/352) | 40.3% (60/149) | |
| > 50% | 16.8% (59/352) | 9.4% (14/149) | |
| Inflow tract stenosis | 0.023 | ||
| None | 41.5% (146/352) | 47.0% (70/149) | |
| ≤ 50% | 39.5% (139/352) | 43.6% (65/149) | |
| > 50% | 19.0% (67/352) | 9.4% (14/149) |
Numbers in parentheses represent number of patients or number of lesions as appropriate