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. 2019 Aug 1;36(1):11–24. doi: 10.1007/s12264-019-00413-5

Fig. 5.

Fig. 5

Influence of temperature on the steady-state activation of hNav1.7 and the W1150R variant. A, C Voltage-dependence of steady-state activation at 25 °C and 38 °C for hNav1.7 (A) and the W1150R variant (C). Curves are Boltzmann fits. B Scatter plots of voltage at half-maximal steady-state activation (V1/2) for the WT at 25 °C and 38 °C (25 °C: − 19.36 ± 1.567, n = 15; 38 °C: − 21.42 ± 1.072, n = 19). D Scatter plots of V1/2 for W1150R at 25 °C and 38 °C (25 °C: − 22.57 ± 1.568, n = 9; 38 °C: − 27.24 ± 1.376, n = 7). Data are the mean ± SEM. *P < 0.05; black, 25 °C; red, 38 °C.