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Oxcarbazepine (OXC) modulates the fast time constants of hNav1.7 and SCN9A variants. A–D Average fast time constants of WT hNav1.7 channels (A), average fast time constants of p.(N641Y) mutant hNav1.7 channels (B), average fast time constant of p.(K655R) mutant hNav1.7 channels (C), and average fast time constant of p.(W1150R) mutant hNav1.7 channels (D) with 120 μmol/L OXC versus membrane potential. Data are the mean ± SEM. *P < 0.05.
