Fig. 2. Analysis of β-amyloid (Aβ) metabolism in β-Sitosterol treated amyloid protein precursor/presenilin 1 (APP/PS1) mice.
(A, B) ELISA of soluble Aβ40 and Aβ42 in hippocampal and cortical samples of APP/PS1 mice. (C, D) ELISA of insoluble Aβ40 and Aβ42 in hippocampal and cortical samples of APP/PS1 mice. Data are presented as mean ± standard error of the mean. n = 9–12 mice per group, gender mixed. One-way ANOVA, Bonferroni multiple comparisons test or Student's t-test were used: ###p < 0.001 vs. wild-type (WT), **p ≤ 0.001 vs. APP/PS1 mice.