Fig. 4. Effects of CAR on depression-like and anxiety-like behaviors in the forced swimming test (FST) and elevated plus maze (EPM) test after LPS injection.

Immobility time (A) in the FST, numbers of entries into the open and closed arms in the EPM test (B and C), and grip strength (D). CAR, carvacrol; LPS, lipopolysaccharide; SAL, saline-treated; IBU, ibuprofen. ^*p < 0.05 and ^**p < 0.01 vs. SAL group; ^#p < 0.05 vs. LPS group.