Figure 2:
(A) Plot of Brillouin shift in the central region (< 1 mm from the corneal apex) vs. central corneal thickness (CCT) for normal subjects (orange) and FECD patients (blue). Dotted line shows a linear fit to the data with a fitted slope [95% confidence interval] of −0.92 [−1.42, −0.42] MHz/μm. (B) Plot of Brillouin regional difference (peripheral minus central) vs. central-to-peripheral thickness ratio (CPTR) for normal subjects (orange) and FECD patients (blue). Dotted line shows a linear fit to the data with a fitted slope [95% confidence interval] of 580 [400, 770] MHz/CPTR.