Table 1.
Baseline characteristics of participants during the run-in and intervention intervals
| Demographics | Run-in interval | Intervention interval |
|---|---|---|
| Number with pillbox data | 136 | 138 |
| Age | 15.8 [13.6–17.4] | 16.0 [13.8–17.6] |
| Male | 83 (61.0) | 84 (60.9) |
| Race | ||
| White | 92 (67.6) | 89 (64.5) |
| Black | 17 (12.5) | 17 (12.3) |
| Other | 27 (19.9) | 32 (23.2) |
| Hispanic or Latino | 12 (8.8) | 12 (8.7) |
| US Study site | 89 (65.5) | 86 (62.3) |
| Healthcare insurer | ||
| U.S. Public | 41 (30.1) | 36 (26.1) |
| U.S. Private | 48 (35.3) | 50 (36.2) |
| Canadian provincial | 47 (34.6) | 52 (37.7) |
| Medication insurer | ||
| U.S. Public | 44 (32.3) | 40 (29.0) |
| Private | 62 (45.6) | 66 (47.8) |
| Canadian provincial | 16 (11.8) | 17 (12.3) |
| Other | 14 (10.3) | 15 (10.9) |
| Household income per year | ||
| Less than $50,000 | 57 (41.9) | 55 (39.9) |
| Greater than $50,000 | 62 (45.6) | 67 (48.6) |
| Unknown/Prefer not to answer | 17 (12.5) | 16 (11.6) |
| Disease characteristics | ||
| Years post-transplant | 2.9 [0.8–7.1] | 3.3 [1.0–7.5] |
| Number of prior transplants (including current one) | ||
| 1 | 123 (90.4) | 125 (90.6) |
| 2 | 13 (9.6) | 13 (9.4) |
| Donor source | ||
| Living | 71 (52.2) | 71 (51.4) |
| Deceased | 65 (47.8) | 67 (48.6) |
| Duration of dialysis before current transplant | ||
| 0 month | 39 (28.7) | 39 (28.3) |
| > 0 month | 97 (71.3) | 99 (71.7) |
| Total lifetime duration of dialysis | ||
| 0 month | 37 (27.2) | 37 (26.8) |
| > 0 month | 99 (72.8) | 101 (73.2) |
| Age at transplant (in years) | 12.0 [8.3–14.9] | 11.9 [8.0–14.9] |
| Primary disease | ||
| CAKUT | 55 (40.4) | 57 (41.3) |
| Glomerulonephritis | 13 (9.6) | 14 (10.1) |
| FSGS | 14 (10.3) | 14 (10.1) |
| Other | 54 (39.7) | 53 (38.4) |
| Number of past acute rejections | ||
| 0 | 109 (80.1) | 110 (79.7) |
| ≥ 1 | 27 (19.9) | 28 (20.3) |
| Comorbidities | ||
| None | 70 (51.5) | 72 (52.2) |
| ≥ 1 | 66 (48.5) | 66 (47.8) |
| Treatment characteristics | ||
| Number of immunosuppressive medications | ||
| 1 | 4 (2.9) | 3 (2.3) |
| 2 | 43 (31.6) | 44 (33.1) |
| 3 | 89 (65.5) | 86 (64.7) |
| Number of doses of immunosuppressive per day | ||
| 1 | 11 (8.1) | 11 (8.3) |
| 2 | 125 (91.9) | 122 (91.7) |
| Total number of medications | 7.0 [5.0-9.0] | 7.0 [5.0-9.0] |
| Total number of doses per day | ||
| 1 | 4 (2.9) | 5 (3.8) |
| 2 | 120 (88.2) | 115 (86.5) |
| 3 or 4 | 12 (8.9) | 13 (9.8) |
In columns, data given as median [interquartile range] or number (%)