Table 1:
None (n=125) |
Mild (n=42) |
Moderate (n=34) |
Severe (n=25) |
p-value | |
---|---|---|---|---|---|
Recipient Age, years, mean (SD) | 54.3 (13.0) | 53.7 (12.3) | 49.9 (13.4) | 49.2 (15.8) | 0.287 |
Recipient Gender | 0.135 | ||||
Female | 44 (35.2) | 18 (42.9) | 13 (38.2) | 15 (60) | |
Male | 81 (64.8) | 24 (57.1) | 21 (61.8) | 10 (40) | |
Recipient Race | 0.528 | ||||
White | 118 (94.4) | 38 (90.5) | 32 (94.1) | 25 (100) | |
African-American | 5 (4) | 4 (9.5) | 2 (5.9) | 0 (0) | |
Asian | 2 (1.6) | 0 (0) | 0 (0) | 0 (0) | |
Transplant Diagnosis | 0.570 | ||||
ILD | 62 (49.6) | 21 (50) | 13 (38.2) | 11 (44) | |
COPD | 30 (24) | 12 (28.6) | 6 (17.6) | 4 (16) | |
CF | 16 (12.8) | 7 (16.7) | 9 (26.5) | 8 (32) | |
A1AT | 5 (4) | 1 (2.4) | 2 (5.9) | 0 (0) | |
PH | 2 (1.6) | 0 (0) | 1 (2.9) | 0 (0) | |
Other | 10 (8) | 1 (2.4) | 4 (8.8) | 2 (8) | |
Recipient CMV Positive | 75 (60) | 23 (54.8) | 14 (41.2) | 15 (60) | 0.258 |
Donor Age, years, mean (SD) | 35.9 (14.9) | 34.6 (13.3) | 38.9 (14.9) | 39.8 (16) | 0.771 |
Donor Male Gender | 85 (68) | 27 (64.3) | 20 (58.8) | 14 (56.0) | 0.585 |
Donor Race | 0.184 | ||||
White | 101 (80.8) | 33 (78.6) | 20 (58.8) | 20 (80) | |
African-American | 23 (18.4) | 9 (21.4) | 14 (41.2) | 5 (20) | |
Asian | 1 (0.8) | 0 (0) | 0 (0) | 0 (0) | |
CMV Mismatch Status | |||||
R−/D− | 28 (22.4) | 8 (19) | 3 (8.8) | 2 (8) | |
R+/D+ | 51 (40.8) | 21 (50) | 8 (23.5) | 11 (44) | |
R+/D− | 24 (19.2) | 2 (4.8) | 6 (17.6) | 4 (16) | 0.005 |
R−/D+ | 22 (17.6) | 11 (26.2) | 17 (50) | 8 (32) | |
Transplant Type | 0.622 | ||||
Single | 6 (4) | 0 (0) | 1 (2.9) | 1 (4) | |
Bilateral | 119 (96) | 42 (100) | 33 (97.1) | 24 (96) | |
Ischemic Time, minutes, mean (SD) | 278.2 (67.6) | 264.3 (73.6) | 289 (65.8) | 288.1 (80.3) | 0.322 |
Induction Therapy | 0.007 | ||||
Basiliximab | 81 (65.3) | 27 (64.3) | 26 (76.5) | 18 (72) | |
ATGAM | 42 (33.9) | 9 (21.4) | 6 (17.6) | 5 (20) | |
Thymoglobulin | 0 (0) | 2 (4.8) | 0 (0) | 0 (0) | |
Other | 1 (0.8) | 3 (7.1) | 1 (2.9) | 1 (4) | |
None | 0 (0) | 1 (2.4) | 1 (2.9) | 1 (4) | |
PGD @ 72hours | 0.602 | ||||
0 | 54 (43.2) | 11 (26.2) | 10 (29.4) | 10 (40) | |
1 | 60 (48) | 26 (61.9) | 20 (58.8) | 11 (44) | |
2 | 8 (6.4) | 4 (9.5) | 2 (5.9) | 3 (12) | |
3 | 3 (2.4) | 1 (2.4) | 2 (5.9) | 1 (4) |