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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Am J Transplant. 2019 Sep 26;20(1):250–261. doi: 10.1111/ajt.15581

Table 3:

Basic Cox Regression Model of Risk of Death after Lung Transplantation

UNIVARIABLE ANALYSIS MULTIVARIABLE ANALYSIS
Variable Hazard Ratio
(95% CI)
p-value Hazard Ratio
(95% CI)
p-value
Degree of Neutropenia (ref: None) 0.020 0.075
 Mild 0.16 (0.02–1.18) 0.072 0.20 (0.03–1.49) 0.117
 Moderate 0.99 (0.42–2.30) 0.975 0.91 (0.39–2.12) 0.823
 Severe 3.26 (1.29–8.21) 0.012 2.97 (1.05–8.41) 0.040
Recipient Age 0.99 (0.98–1.01) 0.524
Recipient Male Gender 1.24 (0.80–1.90) 0.335
Recipient Race 1.41 (0.57–3.48) 0.457
Transplant Diagnosis (ref: COPD) 0.045
 ILD 0.88 (0.52–1.49) 0.623
 CF 1.12 (0.59–2.10) 0.735
 A1AT 2.82 (1.19–6.65) 0.018
 PH 0.88 (0.12–6.58) 0.904
 Other 0.36 (0.11–1.23) 0.103
Donor Age 0.99 (0.98–1.01) 0.933
Donor Male Gender 1.51 (0.95–2.40) 0.079 1.94 (1.02–3.67) 0.043
Donor Race 1.37 (0.86–2.18) 0.178
CMV Mismatch Status (ref: R−/D−) 0.588
 R+/D+ 1.31 (0.69–2.46) 0.407
 R+/D− 1.17 (0.54–2.53) 0.683
 R−/D+ 1.56 (0.80–3.02) 0.188
Transplant Ischemic Time, min 1.00 (0.99–1.01) 0.612
Transplant Type 1.56 (0.38–6.33) 0.537
ACR 0.75 (0.48–1.17) 0.206
CLAD 2.98 (1.82–4.86) <0.001 2.68 (1.42–5.04) 0.002
CMV Infection 1.62 (1.01–2.58) 0.044 1.73 (0.96–3.10) 0.066
Aspergillus Infection 1.72 (1.13–2.63) 0.011
Gram Positive Bacterial Infection 1.43 (0.93–2.19) 0.102
Gram Negative Bacterial Infection 1.70 (1.10–2.64) 0.018 1.87 (1.08–3.24) 0.026