Table 5:
Univariable Analysis | Multivariable Analysis | |||
---|---|---|---|---|
Variable | Hazard Ratio (95% CI) | p-value | Hazard Ratio (95% CI) | p-value |
Recipient Age at Transplant | 0.989 (0.975–1.003) | 0.120 | ||
Recipient Male Gender | 0.700 (0.473–1.035) | 0.074 | 0.654 (0.431–0.992) | 0.046 |
Recipient Race (Black vs. White) | 1.525 (0.668–3.485) | 0.316 | ||
Induction Immunosuppression (ATGAM vs. Simulect) | 0.610 (0.370–1.004) | 0.052 | ||
Recipient Diagnosis (Reference: COPD) |
0.383 | |||
Interstitial Lung Disease | 1.066 (0.640–1.776) | 0.805 | ||
Cystic Fibrosis | 1.696 (0.950–3.028) | 0.074 | ||
Alpha-1 Antitrypsin | 0.878 (0.263–2.938) | 0.833 | ||
Pulmonary Hypertension | 0.658 (0.089–4.880) | 0.682 | ||
Other | 0.870 (0.353–2.146) | 0.762 | ||
Donor Age | 1.001 (0.989–1.015) | 0.822 | ||
Donor Male Gender | 0.786 (0.527–1.171) | 0.236 | ||
Donor Race (Black v. White) | 1.464 (0.947–2.264) | 0.087 | ||
CMV Mismatch Status (Reference R−/D−) |
0.005 | 0.007 | ||
R+/D+ | 1.531 (0.819–2.864) | 0.182 | 1.319 (0.694–2.509) | 0.398 |
R+/D− | 1.016 (0.463–2.227) | 0.969 | 1.016 0.463–2.228) | 0.969 |
R−/D+ | 2.526 (1.337–4.771) | 0.004 | 2.464 (1.293–4.696) | 0.006 |
Transplant Ischemic Time | 1.000 (0.998–1.003) | 0.732 | ||
Transplant Type (Bilateral vs. Single) | 1.526 (0.376–6.191) | 0.554 | ||
PGD Grade at 72 hours (Reference: 0) | 0.525 | |||
Grade 1 | 1.355 (0.875–2.099) | 0.173 | ||
Grade 2 | 1.423 (0.677–2.990) | 0.352 | ||
Grade 3 | 1.534 (0.541–4.348) | 0.420 | ||
Calcineurin Inhibitor (cyclosporine vs. tacrolimus) | 1.817 (0.575–5.746) | 0.309 |