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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Am J Transplant. 2019 Sep 26;20(1):250–261. doi: 10.1111/ajt.15581

Table 5:

Cox Regression Analysis for Predictors of Neutropenia

Univariable Analysis Multivariable Analysis
Variable Hazard Ratio (95% CI) p-value Hazard Ratio (95% CI) p-value
Recipient Age at Transplant 0.989 (0.975–1.003) 0.120
Recipient Male Gender 0.700 (0.473–1.035) 0.074 0.654 (0.431–0.992) 0.046
Recipient Race (Black vs. White) 1.525 (0.668–3.485) 0.316
Induction Immunosuppression (ATGAM vs. Simulect) 0.610 (0.370–1.004) 0.052
Recipient Diagnosis
(Reference: COPD)
0.383
 Interstitial Lung Disease 1.066 (0.640–1.776) 0.805
 Cystic Fibrosis 1.696 (0.950–3.028) 0.074
 Alpha-1 Antitrypsin 0.878 (0.263–2.938) 0.833
 Pulmonary Hypertension 0.658 (0.089–4.880) 0.682
 Other 0.870 (0.353–2.146) 0.762
Donor Age 1.001 (0.989–1.015) 0.822
Donor Male Gender 0.786 (0.527–1.171) 0.236
Donor Race (Black v. White) 1.464 (0.947–2.264) 0.087
CMV Mismatch Status
(Reference R−/D−)
0.005 0.007
 R+/D+ 1.531 (0.819–2.864) 0.182 1.319 (0.694–2.509) 0.398
 R+/D− 1.016 (0.463–2.227) 0.969 1.016 0.463–2.228) 0.969
 R−/D+ 2.526 (1.337–4.771) 0.004 2.464 (1.293–4.696) 0.006
Transplant Ischemic Time 1.000 (0.998–1.003) 0.732
Transplant Type (Bilateral vs. Single) 1.526 (0.376–6.191) 0.554
PGD Grade at 72 hours (Reference: 0) 0.525
 Grade 1 1.355 (0.875–2.099) 0.173
 Grade 2 1.423 (0.677–2.990) 0.352
 Grade 3 1.534 (0.541–4.348) 0.420
Calcineurin Inhibitor (cyclosporine vs. tacrolimus) 1.817 (0.575–5.746) 0.309