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. 2020 Jan;190(1):158–175. doi: 10.1016/j.ajpath.2019.09.023

Figure 2.

Figure 2

A-Raptor KO mice have adipose atrophy without alcohol exposure. A-Raptor KO mice and matched Cre− (WT) mice were subjected to Gao-binge alcohol treatment. A: Representative gross images of epididymal white adipose tissue (eWAT), retroperitoneal WAT (rWAT), and interscapular brown adipose tissue (iBAT). B: Quantification of fat tissue weight of eWAT, rWAT, and iBAT after Gao-binge treatment. C: Representative hematoxylin and eosin (H&E) staining images of eWAT and iBAT. D: Distribution of eWAT adipocyte area from H&E staining. Data are expressed as means ± SEM (B and D). n = 5 to 7 (B). n = 3 to 6 mice per group (D). *P < 0.05 (one-way analysis of variance). Scale bars = 1 cm (A). Original magnification: ×20 (C, eWAT); ×40 (C, iBAT). ETOH, ethanol.