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. 2020 Jan;190(1):158–175. doi: 10.1016/j.ajpath.2019.09.023

Figure 5.

Figure 5

A-Atg5 KO mice are partially resistant to Gao-binge alcohol–induced adipocyte atrophy. A-Atg5 KO mice and matched WT mice were subjected to Gao-binge alcohol treatment. A: Quantification of fat tissue weight to body weight (BW) of s.c. white adipose tissue (sWAT), epididymal WAT (eWAT), retroperitoneal WAT (rWAT), and interscapular brown adipose tissue (iBAT) after Gao-binge alcohol. B: Representative hematoxylin and eosin (H&E) staining images of eWAT and iBAT. C: Distribution of eWAT adipocyte area in H&E staining. D: Quantification of iBAT lipid droplet (LD) area in H&E staining. Data are expressed as means ± SEM (A, C, and D). n = 5 to 17 (A); n = 3 to 6 mice per group (C); n = 4 to 8 mice per group (D). *P < 0.05 (one-way analysis of variance). Original magnification: ×20 (B, eWAT); ×40 (B, iBAT). ETOH, ethanol.