Table 2.
Fractional anisotropy (FA) | Mean diffusivity (MD) | |||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Descriptive statistics | Main effect | Descriptive statistics | Main effect | |||||||||||||||||||||
Group | Age | Sex | Site | Group | Age | Sex | Site | |||||||||||||||||
Mild TBI | OI | Parameter estimate | Mild TBI | OI | Parameter estimate | |||||||||||||||||||
Tract | M | SD | M | SD | B | p | B | p | B | p | B | p | M | SD | M | SD | B | p | B | p | B | p | B | p |
Left Hemisphere | ||||||||||||||||||||||||
AF | 0.50 | 0.04 | 0.49 | 0.03 | <0.01 | .766 | <0.01 | .019 | <0.01 | .705 | −0.02 | <.001 | 0.75 | 0.03 | 0.75 | 0.03 | <0.01 | .601 | <0.01 | .002 | 0.01 | .086 | −0.03 | <.001 |
Cingulum Cingulate | 0.49 | 0.06 | 0.47 | 0.06 | −0.01 | .098 | 0.01 | <.001 | 0.02 | .001 | −0.07 | <.001 | 0.78 | 0.03 | 0.79 | 0.04 | 0.01 | .058 | <0.01 | .006 | <0.01 | .706 | <0.01 | .570 |
Cingulum Hippocampus | 0.36 | 0.04 | 0.37 | 0.04 | 0.01 | .447 | <0.01 | .065 | 0.01 | .403 | −0.05 | <.001 | 0.88 | 0.05 | 0.88 | 0.04 | 0.01 | .589 | <0.01 | .537 | <0.01 | .750 | 0.03 | .002 |
CST | 0.63 | 0.03 | 0.63 | 0.03 | <0.01 | .822 | <0.01 | .003 | <0.01 | .769 | 0.01 | .040 | 0.77 | 0.04 | 0.77 | 0.03 | <0.01 | .403 | <0.01 | <.001 | <0.01 | .976 | −0.04 | <.001 |
IFOF | 0.48 | 0.03 | 0.48 | 0.03 | <0.01 | .381 | <0.01 | .221 | −0.01 | .012 | −0.01 | .015 | 0.83 | 0.03 | 0.83 | 0.02 | <0.01 | .392 | <0.01 | .079 | 0.01 | .001 | <0.01 | .912 |
ILF | 0.42 | 0.03 | 0.42 | 0.03 | <0.01 | .955 | <0.01 | .009 | <0.01 | .830 | −0.02 | <.001 | 0.87 | 0.04 | 0.88 | 0.03 | 0.01 | .135 | <0.01 | .117 | 0.01 | .133 | <0.01 | .829 |
SLF | 0.43 | 0.05 | 0.44 | 0.05 | <0.01 | .533 | <0.01 | .019 | −0.01 | .296 | −0.06 | <.001 | 0.75 | 0.04 | 0.75 | 0.03 | <0.01 | .914 | <0.01 | .010 | 0.01 | .184 | −0.01 | .041 |
Thalamic Radiation | 0.46 | 0.03 | 0.45 | 0.03 | <0.01 | .612 | <0.01 | .039 | 0.01 | .210 | −0.02 | <.001 | 0.76 | 0.03 | 0.77 | 0.02 | 0.01 | .033 | <0.01 | .030 | <0.01 | .647 | 0.01 | .025 |
UF | 0.41 | 0.04 | 0.42 | 0.04 | <0.01 | .448 | <0.01 | .683 | −0.01 | .103 | −0.05 | <.001 | 0.86 | 0.03 | 0.86 | 0.03 | 0.01 | .183 | <0.01 | .232 | <0.01 | .856 | 0.03 | <.001 |
Right Hemisphere | ||||||||||||||||||||||||
AF | 0.47 | 0.04 | 0.47 | 0.04 | <0.01 | .940 | <0.01 | .122 | −0.01 | .223 | <0.01 | .531 | 0.77 | 0.05 | 0.76 | 0.05 | <0.01 | .783 | <0.01 | <.001 | 0.01 | .048 | −0.08 | <.001 |
Cingulum Cingulate | 0.45 | 0.05 | 0.45 | 0.06 | <0.01 | .610 | 0.01 | <.001 | 0.01 | .311 | −0.06 | <.001 | 0.78 | 0.04 | 0.79 | 0.05 | <0.01 | .541 | <0.01 | .018 | 0.02 | .010 | −0.04 | <.001 |
Cingulum Hippocampus | 0.38 | 0.04 | 0.37 | 0.04 | −0.01 | .386 | <0.01 | .269 | 0.01 | .268 | −0.04 | <.001 | 0.86 | 0.05 | 0.87 | 0.05 | 0.01 | .553 | <0.01 | .162 | <0.01 | .636 | 0.01 | .132 |
CST | 0.63 | 0.03 | 0.63 | 0.03 | <0.01 | .688 | <0.01 | <.001 | <0.01 | .969 | 0.02 | <.001 | 0.76 | 0.04 | 0.76 | 0.03 | 0.01 | .250 | <0.01 | .022 | <0.01 | .820 | −0.04 | <.001 |
IFOF | 0.49 | 0.03 | 0.50 | 0.03 | 0.01 | .084 | <0.01 | .028 | −0.01 | .031 | −0.01 | .001 | 0.83 | 0.04 | 0.84 | 0.04 | 0.01 | .117 | <0.01 | .104 | 0.01 | .019 | −0.04 | <.001 |
ILF | 0.43 | 0.04 | 0.43 | 0.04 | <0.01 | .638 | <0.01 | .845 | <0.01 | .716 | −0.02 | .004 | 0.86 | 0.04 | 0.86 | 0.04 | <0.01 | .502 | <0.01 | .006 | 0.01 | .076 | −0.02 | .001 |
SLF | 0.48 | 0.05 | 0.48 | 0.05 | <0.01 | .963 | <0.01 | <.001 | 0.01 | .188 | −0.04 | <.001 | 0.76 | 0.06 | 0.76 | 0.05 | <0.01 | .956 | <0.01 | .005 | 0.01 | .325 | −0.09 | <.001 |
Thalamic Radiation | 0.47 | 0.03 | 0.47 | 0.03 | <0.01 | .861 | <0.01 | .001 | 0.01 | .110 | 0.01 | .005 | 0.76 | 0.03 | 0.77 | 0.03 | 0.01 | .020 | <0.01 | .444 | <0.01 | .409 | −0.03 | <.001 |
UF | 0.43 | 0.03 | 0.43 | 0.03 | <0.01 | .683 | <0.01 | .090 | <0.01 | .384 | −0.02 | <.001 | 0.85 | 0.04 | 0.85 | 0.04 | 0.01 | .195 | <0.01 | .024 | <0.01 | .684 | −0.03 | <.001 |
Corpus Callosum | ||||||||||||||||||||||||
Splenium | 0.61 | 0.05 | 0.62 | 0.05 | 0.01 | .252 | <0.01 | .039 | <0.01 | .607 | −0.02 | .019 | 0.92 | 0.09 | 0.91 | 0.07 | −0.02 | .209 | −0.01 | .034 | 0.02 | .207 | 0.01 | .301 |
Genu | 0.58 | 0.03 | 0.58 | 0.02 | <0.01 | .936 | <0.01 | .595 | <0.01 | .417 | −0.01 | .012 | 0.81 | 0.03 | 0.82 | 0.03 | <0.01 | .598 | <0.01 | .027 | <0.01 | .295 | −0.02 | <.001 |