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. 2019 Dec 13;25:102106. doi: 10.1016/j.nicl.2019.102106

Table 2.

Descriptive statistics and multivariable linear regression results examining group differences on white matter microstructure of examined tracts for Aim 1. Note. Italic = unadjusted p-value < .05; Bolded = FDR adjusted p-value < .05. AF = arcuate fasciculus; CST = Corticospinal Tract ; IFOF = inferior frontal-occipital fasciculus; SLF = superior longitudinal fasciculus; UF = uncinate fasciculus.

Fractional anisotropy (FA) Mean diffusivity (MD)
Descriptive statistics Main effect Descriptive statistics Main effect
Group Age Sex Site Group Age Sex Site
Mild TBI OI Parameter estimate Mild TBI OI Parameter estimate
Tract M SD M SD B p B p B p B p M SD M SD B p B p B p B p
Left Hemisphere
 AF 0.50 0.04 0.49 0.03 <0.01 .766 <0.01 .019 <0.01 .705 −0.02 <.001 0.75 0.03 0.75 0.03 <0.01 .601 <0.01 .002 0.01 .086 −0.03 <.001
 Cingulum Cingulate 0.49 0.06 0.47 0.06 −0.01 .098 0.01 <.001 0.02 .001 −0.07 <.001 0.78 0.03 0.79 0.04 0.01 .058 <0.01 .006 <0.01 .706 <0.01 .570
 Cingulum Hippocampus 0.36 0.04 0.37 0.04 0.01 .447 <0.01 .065 0.01 .403 −0.05 <.001 0.88 0.05 0.88 0.04 0.01 .589 <0.01 .537 <0.01 .750 0.03 .002
 CST 0.63 0.03 0.63 0.03 <0.01 .822 <0.01 .003 <0.01 .769 0.01 .040 0.77 0.04 0.77 0.03 <0.01 .403 <0.01 <.001 <0.01 .976 −0.04 <.001
 IFOF 0.48 0.03 0.48 0.03 <0.01 .381 <0.01 .221 −0.01 .012 −0.01 .015 0.83 0.03 0.83 0.02 <0.01 .392 <0.01 .079 0.01 .001 <0.01 .912
 ILF 0.42 0.03 0.42 0.03 <0.01 .955 <0.01 .009 <0.01 .830 −0.02 <.001 0.87 0.04 0.88 0.03 0.01 .135 <0.01 .117 0.01 .133 <0.01 .829
 SLF 0.43 0.05 0.44 0.05 <0.01 .533 <0.01 .019 −0.01 .296 −0.06 <.001 0.75 0.04 0.75 0.03 <0.01 .914 <0.01 .010 0.01 .184 −0.01 .041
 Thalamic Radiation 0.46 0.03 0.45 0.03 <0.01 .612 <0.01 .039 0.01 .210 −0.02 <.001 0.76 0.03 0.77 0.02 0.01 .033 <0.01 .030 <0.01 .647 0.01 .025
 UF 0.41 0.04 0.42 0.04 <0.01 .448 <0.01 .683 −0.01 .103 −0.05 <.001 0.86 0.03 0.86 0.03 0.01 .183 <0.01 .232 <0.01 .856 0.03 <.001
Right Hemisphere
 AF 0.47 0.04 0.47 0.04 <0.01 .940 <0.01 .122 −0.01 .223 <0.01 .531 0.77 0.05 0.76 0.05 <0.01 .783 <0.01 <.001 0.01 .048 −0.08 <.001
 Cingulum Cingulate 0.45 0.05 0.45 0.06 <0.01 .610 0.01 <.001 0.01 .311 −0.06 <.001 0.78 0.04 0.79 0.05 <0.01 .541 <0.01 .018 0.02 .010 −0.04 <.001
 Cingulum Hippocampus 0.38 0.04 0.37 0.04 −0.01 .386 <0.01 .269 0.01 .268 −0.04 <.001 0.86 0.05 0.87 0.05 0.01 .553 <0.01 .162 <0.01 .636 0.01 .132
 CST 0.63 0.03 0.63 0.03 <0.01 .688 <0.01 <.001 <0.01 .969 0.02 <.001 0.76 0.04 0.76 0.03 0.01 .250 <0.01 .022 <0.01 .820 −0.04 <.001
 IFOF 0.49 0.03 0.50 0.03 0.01 .084 <0.01 .028 −0.01 .031 −0.01 .001 0.83 0.04 0.84 0.04 0.01 .117 <0.01 .104 0.01 .019 −0.04 <.001
 ILF 0.43 0.04 0.43 0.04 <0.01 .638 <0.01 .845 <0.01 .716 −0.02 .004 0.86 0.04 0.86 0.04 <0.01 .502 <0.01 .006 0.01 .076 −0.02 .001
 SLF 0.48 0.05 0.48 0.05 <0.01 .963 <0.01 <.001 0.01 .188 −0.04 <.001 0.76 0.06 0.76 0.05 <0.01 .956 <0.01 .005 0.01 .325 −0.09 <.001
 Thalamic Radiation 0.47 0.03 0.47 0.03 <0.01 .861 <0.01 .001 0.01 .110 0.01 .005 0.76 0.03 0.77 0.03 0.01 .020 <0.01 .444 <0.01 .409 −0.03 <.001
 UF 0.43 0.03 0.43 0.03 <0.01 .683 <0.01 .090 <0.01 .384 −0.02 <.001 0.85 0.04 0.85 0.04 0.01 .195 <0.01 .024 <0.01 .684 −0.03 <.001
Corpus Callosum
 Splenium 0.61 0.05 0.62 0.05 0.01 .252 <0.01 .039 <0.01 .607 −0.02 .019 0.92 0.09 0.91 0.07 −0.02 .209 −0.01 .034 0.02 .207 0.01 .301
 Genu 0.58 0.03 0.58 0.02 <0.01 .936 <0.01 .595 <0.01 .417 −0.01 .012 0.81 0.03 0.82 0.03 <0.01 .598 <0.01 .027 <0.01 .295 −0.02 <.001