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. 2019 Dec 23;30:101412. doi: 10.1016/j.redox.2019.101412

Fig. 2.

Fig. 2

Nrf2(L)-KO female mice show reduced liver enlargement, milder hepatic steatosis and lower hepatic TG accumulation than Nrf2-LoxP mice fed with HFD. (A) Heart mass and (B) organ mass index expressed as a fold of heart. n = 10 for Nrf2-LoxP, CD; n = 11 for Nrf2(L)-KO, CD; n = 8 for Nrf2-LoxP, HFD; n = 7 for Nrf2(L)-KO, HFD. Values are mean ± SD. *p < 0.05 vs. CD of the same genotype; #p < 0.05 vs. Nrf2-LoxP mice with the same diet. (C–E) Levels of TG, glycerol and FFA in plasma. n = 5 for Nrf2-LoxP, CD; n = 5 for Nrf2(L)-KO, CD; n = 8 for Nrf2-LoxP, HFD; n = 7 for Nrf2(L)-KO, HFD. (F–H) Levels of hepatic TG (F), glycerol (G) and FFA (H). n = 7–11 for TG contents; n = 5–8 for glycerol and FFA measurements. (I) Representative histological images of H&E and Oil Red O staining in the liver. Magnification = 100 × ; bar scale = 300 μm. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)