Table 2.
Fitted Stochastic Cox PH Model for Overall Survival Time of CRC Patients (770 Patients, 99 Deaths for CRC).
| Predictors | Coef | SE (Coef) | HR∗ | 95% CI for HR | p |
|---|---|---|---|---|---|
| Age | 0.022 | 0.010 | 1.02 | (1.00; 1.04) | 0.039 |
| pTNM Stage | |||||
| T = In situ, I, II, III; baseline | – | – | – | – | – |
| T = IV | 0.681 | 0.242 | 1.98 | (1.23; 3.18) | 0.005 |
| Histopathology Grade | |||||
| Grade I (well differentiated; baseline) | – | – | – | – | – |
| Grade II (moderately differentiated) | 0.333 | 0.330 | 1.40 | (0.73; 2.67) | 0.313 |
| Grade III (poorly differentiated) | 0.983 | 0.390 | 2.67 | (1.25; 5.73) | 0.012 |
| Metastases in Lymphatic Nodes | |||||
| Without metastases; baseline | – | – | – | – | – |
| With metastases | 1.145 | 0.248 | 3.14 | (1.93; 5.11) | <0.001 |
| Distant Metastases | |||||
| Without metastases; baseline | – | – | – | – | – |
| At least one metastasis at resection time | 1.764 | 0.267 | 5.84 | (3.46; 9.85) | <0.001 |
| At least one metastasis later | 1.215 | 0.256 | 3.37 | (2.04; 5.57) | <0.001 |
Score (log-rank overall) test: p < 0.001.
SE, standard error; CI, confidence interval; HR, hazard ratio.
∗
A positive (negative) coefficient estimate in the Cox PH model corresponds to a higher (lower) risk of death and thus on average a shorter (longer) OS time.