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. 2019 Dec 5;20(24):6125. doi: 10.3390/ijms20246125

Figure 2.

Figure 2

AnxA2 deficiency increases expression of pro-inflammatory cytokine and adhesion molecules in the brain after TBI. (A) Quantitative analysis of TNFα mRNA levels in the cortex area of ipsilateral hemisphere in WT and Annexin A2 knockout (A2KO) mice at day one after controlled cortical impact (CCI). (B) Quantitative analysis of IL-1β mRNA levels in the cortex area of ipsilateral hemisphere in WT and A2KO mice at day one after CCI. (C) Representative gel images of Western blotting for VCAM1, E-selectin, AnxA2, Ly6G, and β-actin expression at day two after CCI. (D) Quantification of Western blotting for VCAM1 expression. (E) Quantification of Western blotting for E-selectin. (F) Quantification of Western blotting for Ly6G. Data are expressed as mean ± SEM; n = 4, * p < 0.05 compared to WT-sham, # p < 0.05 compared to A2KO-sham, & p < 0.05 compared to WT-CCI.