AnxA2 deficiency worsens neurological outcomes after TBI. WT and A2KO mice were subjected to sham injury or TBI. (A) Modified neurological severity score (NSS). (B) Grip test. (C) Food fault test. (D) Rota Rod test. (E,F) Morris Water maze. (G,H) Y-maze test was performed to assess neurobehavioral outcome up to 28 days after TBI. Sample sizes were WT-sham, n = 8; WT-TBI, n = 12; A2KO-sham, n = 10; A2KO-TBI, n = 13, respectively. Data are expressed as mean ± SEM; * p < 0.05 compared to WT-sham, #
p < 0.05 compared to A2KO-sham, &
p < 0.05 compared to WT-TBI, $
p < 0.05 compared to WT-sham.