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. 2019 Dec 11;20(24):6239. doi: 10.3390/ijms20246239

Figure 5.

Figure 5

The apoptosis and the expression of relative proteins. (A) The cytoplasmic cyt c level of HL-60 cells after 24 h incubation with PDT-BIPA. Pretreatment of the apoptosis inhibitor ZVAD-fmk ahead 12 h could partially cut down the apoptotic percentage (B) while the necrosis inhibitor NEC-1 could not (C). The protein expression of HL-60 cells altered after the exposure to PDT-BIPA (0.5, 1, 2 µM) for 18 h or 24 h (D). And the tumor protein expression showed the same tendency after four times PDT-BIPA treatment (0.8 mg/kg or 1.6 mg/kg) (E).