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Local and systemic levels of HMGB1. The local HMGB1 levels in the ileum (A) and systemic HMGB1 levels in plasma (B) were measured in the gnotobiotic piglets by ELISA. Results are expressed as mean + SEM. Differences between the control GF group and other groups were evaluated by one-way analysis of variance (ANOVA) with Dunnett’s multiple comparison post-hoc test and depicted * p ˂ 0.05, ** p ˂ 0.01, *** p ˂ 0.001; n = 6 for each group.
