| BBB | Blood brain barrier |
| LOC | Lab-on-a-chip |
| TEER | Transendothelial Electrical Resistance |
| NMs | Nanomedicines |
| SLNs | Solid lipid nanoparticles |
| NPs | Nanoparticles |
| CSF | Cerebrospinal fluid |
| AD | Alzheimer’s disease |
| PD | Parkinson’s disease |
| HD | Huntington’s disease |
| BVD | Brain vessel density |
| BMECs | Brain microvascular endothelial cells |
| VEGF | Vascular endothelial growth factor |
| NO | Nitric oxide |
| CsA | Cyclosporine A |
| mPEG-PLGA | Methoxy poly(ethylene glycol)-b-poly(lactic-co-glycolic acid) |
| BVZ | Bevacizumab |
| TMZ | Temozolomide |
| DOX | Doxorubicin |
| SFN | Sorafenib |
| GBM | Glioblastoma multiforme |
| ApoE | Apolipoprotein E |
| MTX | Methotrexate |
| CTX | Chlorotoxin |
| PC | Parallel channel |
| HT | hollow-microtube |
| CR | Concentric-ring |
| PMA | Phorbol 12-myristate 13-acetate |
| S1P | Sphingosine-1-phosphate |
| GFAP | Glial fibrillary acidic protein |
| PDMS | Polydimethylsiloxane |
| P-gp | Permeability glycoprotein |
| HUVEC | Human Umbilical Vein Endothelial Cell |
| hCMEC | Human Cerebral Microvascular Endothelial Cell |
| iPS-BMVEC | Induced pluripotent stem cell-derived human brain microvascular endothelial cell |
| hBMVEC | Human brain microvascular endothelial cells |
| RBE4 | Rat brain endothelial cell 4 |
| b.End3 | Mice brain endothelial cell |
| hA | Human Astrocyte |
| hP | Human brain Pericyte |
| hNSC | Human neuronal stem cell |
| HIP-009 | Human Hippocampal Neural Stem |
| C8D1A | Mice astrocyte cell |
| LF | Human Lung fibroblast |