Figure 2.
Effect of Toll-like receptor (TLR) stimulation on CD180 protein and mRNA expression. (A) CD180 expression of unstimulated (control), CpG, anti-CD180 antibody-stimulated, and anti-CD180 + CpG-treated (24 h) tonsillar B cells (mean fluorescence intensity, MFI). (B) CD180 mRNA expression in tonsillar B cells following CpG, anti-CD180, and anti-CD180 + CpG stimulation (24 h). Changes in gene expression are shown as RQ values, normalized to unstimulated controls. The horizontal line (value 1) represents the CD180 mRNA of unstimulated control samples. Data are shown as mean ± SEM, n = 4, * p < 0.05.