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Induction of natural autoantibody production by TLR stimulation. Anti-citrate synthase IgM and (A) anti-DNA topoisomerase I IgM (B) production of B cells stimulated with CpG, anti-CD180 antibody, or anti-CD180 + CpG, or left unstimulated (control). Data are presented as means ± SEM, n = 3, * p < 0.05.
