Table 2.
Logistic Regression on Baseline MPI Influencing Mortality Risk in Hospitalized Older Patients
| Outcome | Events/Total (%) | Estimates | MPI at Admission | ||||
|---|---|---|---|---|---|---|---|
| Mild Risk | Moderate Risk | Severe Risk | Increase in 0.1 Point | AUC† (95% CI) | |||
| Overall (in-hospital + post discharge) mortality | 358/1,140 (31.4) | Adjusted risk (95% CI) | 8.0% (3.7–12.2) | 22.4% (18.3–26.5) | 48.2% (42.7–53.7) | OR = 1.60 (1.45–1.76) p < .001 |
0.77 (0.74–0.80) |
| Odds ratio, OR (95% CI) | reference | 3.32 (1.79–6.17) | 10.72 (5.70–20.18) | ||||
| p-value, OR | reference | p < .001 | p < .001 | ||||
| In-hospital mortality | 75/1,140 (6.6) | Adjusted risk (95% CI) | 0.7% (0.0–1.7) | 2.5% (1.2–3.9) | 6.4% (3.9–9.0) | OR = 1.54 (1.29–1.86) P < .001 |
0.79 (0.73–0.85) |
| Odds ratio, OR (95% CI) | reference | OR = 3.78 (0.81–17.66) | OR = 9.99 (2.18–45.80) | ||||
| p-value, OR | reference | p = .09 | p = .003 | ||||
| Postdischarge (1-year) follow-up mortality | 283/1,004‡(31.4) | Adjusted risk (95% CI) | 6.9% (3.0–10.9) | 19.1% (15.2 – 23.0) | 42.8% (37.1–48.5) | OR = 1.57 (1.42–1.74) p < .001 |
0.76 (0.73–0.79) |
| Odds ratio, OR (95% CI) | reference | OR = 3.17 (1.64–6.13) | OR = 10.04 (5.12–19.68) | ||||
| p-value, OR | reference | p = .001 | p < .001 | ||||
Notes: All data (except for AUCs) are reported as odds ratios (ORs) are adjusted for age, gender, center, and primary diagnosis. AUC = area under the curve; CI = confidence intervals; MPI = Multidimensional Prognostic Index.
†AUCs were related to model with MPI in category.
‡75 participants were dead during hospitalization and 61 were lost at the follow-up.