Table 1.
DRP | Endpoint | 3 µM | 1 µM | 300 nM | 100 nM | 30 nM | 10 nM |
---|---|---|---|---|---|---|---|
Day 14 | **** | ns | **** | **** | **** | **** | |
GR15 | Day 21 | **** | **** | **** | **** | **** | **** |
Day 28 | **** | **** | **** | **** | **** | **** | |
Day 14 | ** | ns | **** | **** | *** | **** | |
PR15 | Day 21 | **** | **** | **** | **** | **** | **** |
Day 28 | **** | **** | **** | **** | **** | **** | |
Day 14 | ns | ns | ns | ns | *** | ns | |
PA15 | Day 21 | ns | ns | ns | ns | ** | ns |
Day 28 | ns | ns | ns | ns | **** | ns | |
Day 14 | ns | ns | ns | * | ns | ns | |
GP15 | Day 21 | ns | ns | ns | ns | ns | ns |
Day 28 | ns | * | ns | * | ns | ns |
1 * denotes p < 0.05, ** denotes p < 0.01, *** denotes p < 0.001, and **** denotes p < 0.0001 comparing changes in WST-1 absorbance at each differentiation endpoint (day 14, day 21, day 28) to values at day 7 endpoint by two-way ANOVA analysis of variance followed by Dunnett’s test.