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. 2019 Dec 10;20(24):6233. doi: 10.3390/ijms20246233

Figure 4.

Figure 4

Effects of plasma EVs derived from healthy (CO), OSA-NC(−), and OSA-NC(+) children on endothelial monolayer barrier integrity using endothelial cells originating from multiple vascular beds. Individual cells were seeded at 0 h at density of 50,000 cells into ECIS system arrays (8W10E) for 24 h, then EVs derived from CO, (n = 6), OSA-NC(−), (n = 12), and OSA-NC(+), (n = 12) were added and monitored for another 48 h. * indicates statistical significance, * p < 0.01, ** p < 0.001. Data was recorded by an ECIS Z-theta instrument equipped with ECIS software.