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. 2019 Dec 12;20(24):6282. doi: 10.3390/ijms20246282

Figure 1.

Figure 1

Impact of resveratrol (RSV) on leptin signalling in human hepatoma (HepG2) cells. pSTAT3 activation and triglyceride (TAG) content were determined in palmitate (Palm)-induced steatotic HepG2 cells treated with RSV for (A) and (B) 20 min, (C) and (D) 6 h, and (E) and (F) 24 h. Leptin signalling was activated by the addition of 10 ng/mL leptin during the last 20 min of incubation. * indicates p < 0.05 when comparing the 0 µM RSV group to the control group and # indicates p < 0.05 when comparing 1, 5, 10 or 50 µM RSV groups to the 0 µM RSV group as assessed by Student’s t-test. Data are expressed as the mean ± SD of three replicates. A representative WB image for each RSV incubation time is also included.