Skip to main content
. 2019 Dec 15;20(24):6326. doi: 10.3390/ijms20246326

Table 1.

Conventional markers used for the detection of progenitor cells or the dedifferentiation of tubular epithelial cells. Markers, which are used for progenitor cells detection, are partially different for human and rodent kidneys. Foxm1 is the only marker specific for dedifferentiation. Other markers are used both for dedifferentiated cells and progenitor cells and not selective. Empty fields indicate that the marker was not reported for specified conditions.

Marker Progenitor Cells Dedifferentiation
Human Rodents
Markers of progenitor cells ALDH1 [18,25] - -
BrdU retention Not applicable [13,26,27,28] -
CD24 [16,17,18,25,29,30,31] [15] -
CD44 [30,32] [33] -
CD73 [30,32] - -
CD133 [16,17,18,29,30,31,32,34] Not applicable -
C-kit - [14,35] -
Musculin - [36] -
NCAM1 [37] - -
NFATc1 - [38] -
S100A6 [16,18,25] - -
Sall1 [25,37] [39] -
Sca-1 - [14,15,35,36,40] -
SIX2 [37,41] - -
Marker of dedifferentiation Foxm1 - - [42,43]
Non-selective markers Nestin [44] [35] [45]
Pax-2 [25,30,32,34,37,44] [14,33,35,46] [8,11,47,48,49]
Sox9 - [50] [42,51]
Vimentin [16,17,18,25,30,31,44] [13,14,26,33,35] [9,42,47,48,52,53]