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. Author manuscript; available in PMC: 2020 Jan 3.
Published in final edited form as: J Med Chem. 2018 Mar 6;61(6):2422–2446. doi: 10.1021/acs.jmedchem.7b01664

Figure 6:

Figure 6:

GABAAR α6β3γ2 subtype activity of “D-ring” ortho-OCD3 isomer 8ma

aTwo-point electrophysiological experiments displayed that ligand 8m with a “D-ring” ortho-OCD3 substituent and “A-ring” 8-chloro substituent had no activity at the GABAAR α6β3γ2 subtype.