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GABAAR α6β3γ2 subtype selectivity of the N-hetero ligand 13ca
aConcentration response curves of the change of GABA EC3 currents (modulation, referenced to 100% for the EC3 current) by increasing compound concentrations. Ligand 13c preferentially modulated GABA currents of α6β3γ2 receptors. In the α1-5β3γ2 receptors, lack of activity was confirmed in two-point experiments.
