Fig. 5.

Impact of stickiness heterogeneity on sequence adaptation to high abundance in yeast. Distributions of average stickiness (y-axis) within disordered regions of yeast proteins (standard data set) are displayed as violin shapes. Proteins with low (< 15 ppm, bins 1–4) or high abundance (> 25 ppm, bins 6–10) are further divided based on their stickiness heterogeneity (Δ). Stickiness heterogeneity is defined as the difference between the maximum local stickiness within a 41-residues window and the average IDR-stickiness of the protein. Homogeneous and heterogeneous proteins are those with the 25% lowest and highest Δ, respectively. P values are based on the Wilcoxon test. The number of proteins is given for each class.