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. 2019 Dec 6;431(24):4978–4992. doi: 10.1016/j.jmb.2019.08.008

Fig. 7.

Fig. 7

Hypothetical impact of heterogeneous stickiness on binary interactions versus aggregation. A non-sticky region is not expected to shield a distal sticky region from promiscuous binary interactions (left). However, a non-sticky region may inhibit self-interactions leading to aggregation, if this process involves burying the non-sticky region in a desolvated environment (right).