. 2020 Jan 2;18:2. doi: 10.1186/s12955-019-1255-1

Table 2.

List of instruments included in the item library

Generic Instruments	Disease-Specific Instruments
• DETERMINE Your Nutritional Health Checklist [26] • EuroQoL 5-Dimension (EQ-5D) Instrument [27] • Medical Outcomes Study Family and Marital Functioning Measures [28] • 12-item General Health Questionnaire (GHQ-12) [29] • Health Utilities Index (HUI) [30] • Lequesne Algofunctional Index^b [31] • Life Satisfaction Index (LSI) [32] • Oxford Knee Score (OKS) [33] • Physical Self-Maintenance Scale (PSMS) [34] • Positive Mental Health (PMH) Instrument [18] • Satisfaction with Life Scale (SWLS) [35] • 36-Item Short Form Health Survey (SF-36) [36] • Singapore Successful Aging Questionnaire^b [37] • Singapore Mental Wellbeing (SMWEB) Scale [19] • Patient-Reported Outcomes Measurement Information System (PROMIS) Instrument^a [11]	• Beck Anxiety Inventory (BAI) [38] • Caregiver Quality of Life Index-Cancer (CQOLC) [39] • Center for Epidemiologic Studies Depression Scale (CES-D) [40] • NCCN Distress Thermometer and Problem List [41] • European Organisation for Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC QLQ-C30) [42] • Functional Assessment of Cancer Therapy - Breast (FACT-B) [43] • Functional Assessment of Cancer Therapy - Gastric (FACT-Ga) [44] • Functional Assessment of Cancer Therapy - General (FACT-G) [45] • Functional Living Index-Cancer (FLIC)^b [46, 47] • 36-item Glaucoma Quality of Life (Glau-QoL-36) Questionnaire [48] • Hepatitis Quality of Life Questionnaire (HQLQ)^b [49] • 30-Item Hemifacial Spasm Questionnaire (HFS-30) [50] • Hospital Anxiety and Depression Scale (HADS) [51] • Kidney Disease Quality of Life Short Form™ (KDQOL-SF™) [52] • Knee injury and Osteoarthritis Outcome Score (KOOS)^bc [7] • Medical Outcomes Study HIV Health Survey (MOS-HIV) [53] • Parkinson’s Disease Questionnaire (PDQ-39) [54] • Quality of Life–Alzheimer’s Disease (QOL-AD) Scale [55] • Rheumatology Attitudes Index (RAI) [56] • Schizophrenia Quality of Life Scale (SQLS) [57] • Scleroderma Health Assessment Questionnaire (SHAQ)^b [58] • State-Trait Anxiety Inventory (STAI) [59] • Systemic Sclerosis Quality of Life Scale (SSc-QoL) [60]

Generic Instruments

Disease-Specific Instruments

• DETERMINE Your Nutritional Health Checklist [26]

• EuroQoL 5-Dimension (EQ-5D) Instrument [27]

• Medical Outcomes Study Family and Marital Functioning Measures [28]

• 12-item General Health Questionnaire (GHQ-12) [29]

• Health Utilities Index (HUI) [30]

• Lequesne Algofunctional Index^b [31]

• Life Satisfaction Index (LSI) [32]

• Oxford Knee Score (OKS) [33]

• Physical Self-Maintenance Scale (PSMS) [34]

• Positive Mental Health (PMH) Instrument [18]

• Satisfaction with Life Scale (SWLS) [35]

• 36-Item Short Form Health Survey (SF-36) [36]

• Singapore Successful Aging Questionnaire^b [37]

• Singapore Mental Wellbeing (SMWEB) Scale [19]

• Patient-Reported Outcomes Measurement Information System (PROMIS) Instrument^a [11]

• Beck Anxiety Inventory (BAI) [38]

• Caregiver Quality of Life Index-Cancer (CQOLC) [39]

• Center for Epidemiologic Studies Depression Scale (CES-D) [40]

• NCCN Distress Thermometer and Problem List [41]

• European Organisation for Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC QLQ-C30) [42]

• Functional Assessment of Cancer Therapy - Breast (FACT-B) [43]

• Functional Assessment of Cancer Therapy - Gastric (FACT-Ga) [44]

• Functional Assessment of Cancer Therapy - General (FACT-G) [45]

• Functional Living Index-Cancer (FLIC)^b [46, 47]

• 36-item Glaucoma Quality of Life (Glau-QoL-36) Questionnaire [48]

• Hepatitis Quality of Life Questionnaire (HQLQ)^b [49]

• 30-Item Hemifacial Spasm Questionnaire (HFS-30) [50]

• Hospital Anxiety and Depression Scale (HADS) [51]

• Kidney Disease Quality of Life Short Form™ (KDQOL-SF™) [52]

• Knee injury and Osteoarthritis Outcome Score (KOOS)^bc [7]

• Medical Outcomes Study HIV Health Survey (MOS-HIV) [53]

• Parkinson’s Disease Questionnaire (PDQ-39) [54]

• Quality of Life–Alzheimer’s Disease (QOL-AD) Scale [55]

• Rheumatology Attitudes Index (RAI) [56]

• Schizophrenia Quality of Life Scale (SQLS) [57]

• Scleroderma Health Assessment Questionnaire (SHAQ)^b [58]

• State-Trait Anxiety Inventory (STAI) [59]

• Systemic Sclerosis Quality of Life Scale (SSc-QoL) [60]

^aIncluded PROMIS domain instruments listed in Additional file 3

^bInstruments which are locally-adapted versions of HRQOL instruments originally developed outside of Singapore

^c The KOOS includes the Western Ontario and McMaster Universities (WOMAC) Osteoarthritis in its complete and original format [61] [62]. For purposes of this study, the WOMAC was considered a subset of the KOOS